You are kindly invited to participate in the EMBO | EMBL 2012 Symposia with the main topic of "Germline - Immortality through Totipotency", taking place in Heidelberg, Germany 13-16 October, 2012. The event is organised by the European Molecular Biology Laboratory (EMBL).
What does immortality mean at the molecular, cellular, transgenerational and evolutionary level?
Most organisms have a defined lifespan, however life of a species continues and evolves via germline from generation to generation. Recent studies show that tissue stem cells share molecular and developmental signatures with the germline and that even fully differentiated, postmitotic cells can be reprogrammed to regain totipotency.
This EMBO | EMBL Symposium will go beyond a description of the phenomena involving stem cell behaviour, programming and reprogramming. It will bring together researchers from different disciplines, who will address fundamental questions of totipotency as they relate to evolution, development and tissue specialization.
Questions to be discussed
- how a need for germline specification arose during the evolution of multicellularity from single cells to colonies with specialized cell types;
- how the fertilized egg cell loses totipotency during formation of a multicelluar organism;
- how chromatin-based mechanisms influence totipotency both at the cellular and transgenerational level; and
- how the decision toward meiosis is achieved and regulated.
- From single cells to multicellularity
- Keeping it all together: chromosomes and chromatin
- Programming and reprogramming
- Conservative vs progressive divisions (mitosis and meiosis)
- Context matters
- Angelika Amon, Professor of Biology, The Koch Institute, Massachusetts Institute of Technology (MIT), USA
- John Gurdon, Wellcome Trust/Cancer Research UK Gurdon Institute, CRUK Institute, University of Cambridge, United Kingdom
- Azim Surani, Professor of Physiology and Reproduction, Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, United Kingdom
Registration Fee Waivers and Travel Grants
Registration fee waivers and travel grants for young researchers residing in eligible countries are available. Please indicate your interest when submitting your abstract. During the abstract submission phase (step 2 after you have registered for the conference) there will be a small field to complete your reasons for requesting this registration fee waiver or travel grant.
Both, fee waivers and travel grants will be distributed at the discretion of the scientific organisers during the abstract review. If you are awarded, you will be notified after the abstract review has been completed and asked to confirm your acceptance. This is usually two months before the conference start date. Under these circumstances, you either would not be requested to pay the registration fee for the course (registration fee waiver) or the EMBL Course and Conference office will request your bank details and will transfer a fixed sum to your bank account after the conference has taken place (travel grant). If you have already paid your registration fee by this date, the Course and Conference Office will request your bank details and will reimburse the registration fee.