EMBO | EMBL Symposium on Tumour Microenvironment and Signalling 2016 Heidelberg

  • Conference Call
  • Euro­pean Mol­e­c­u­lar Biol­ogy Lab­o­ra­tory (EMBL) is happy to announce the 2016 Edi­tion of its Sym­po­sium on Tumour Microen­vi­ron­ment and Sig­nalling to com­mence on April 36, 2016 tak­ing place in Hei­del­berg, Ger­many.

    Event Descrip­tion

    Many onco­genes and tumour sup­pres­sor genes have been iden­ti­fied and mapped to sig­nalling path­ways that reg­u­late cell growth and death. Dys­reg­u­la­tion allows onco­genes and tumour sup­pres­sor genes to trans­form mam­malian cells and can­cers arise in con­di­tions where mul­ti­ple such events occur in the same cell.

    Many proto-​oncogenes and tumour sup­pres­sors have been mapped to canon­i­cal sig­nalling path­ways, pro­vid­ing a more holis­tic view of growth con­trol mech­a­nisms and paving the way for sys­tems level analy­sis of can­cer mech­a­nisms. It has also been found that a sub­set of the cells present in a tumour, called can­cer stem cells, retain the abil­ity to self-​renew and to give rise to all cell types in a par­tic­u­lar can­cer. An emerg­ing con­cept is that tumours also strongly depend on exter­nal sig­nals for main­te­nance and expansion.

    To fully under­stand tumour devel­op­ment and pro­gres­sion, a deeper knowl­edge of the cross-​talk between tumour cells and their microen­vi­ron­ment and the inter­ac­tions between can­cer cells and can­cer stem cells is needed.

    Keynote Speak­ers

    • Sean J. Mor­ri­son – The Uni­ver­sity of Texas South­west­ern Med­ical Cen­ter, USA
    • Charles Swan­ton – The Fran­cis Crick Insti­tute, Uni­ver­sity Col­lege Lon­don, UK

    Aims of event

    This sym­po­sium brings together researchers from com­ple­ment­ing fields to enhance our under­stand­ing of the com­mu­ni­ca­tion between can­cer cells and their microen­vi­ron­ment. Impor­tant open ques­tions are: Which sig­nals do can­cer cells trans­mit to and receive from the stroma and how do these sig­nals pro­mote malig­nant growth? What roles does the extra­cel­lu­lar matrix play dur­ing neo­plas­tic trans­for­ma­tion? What is the con­tri­bu­tion of immune cells to tumour pro­gres­sion? How is the inflam­ma­tory response of the tumour microen­vi­ron­ment reg­u­lated by the microbiota?

    Con­firmed Speakers

    • Ravi K. Ama­r­avadi – Perel­man School of Med­i­cine, Uni­ver­sity of Penn­syl­va­nia, USA
    • Eduard Batlle – Insti­tute for Research in Bio­med­i­cine (IRB), Spain
    • Judith Camp­isi – Buck Insti­tute for Research on Aging, USA
    • Vin­cenzo Cerun­dolo – Uni­ver­sity of Oxford, United Kingdom
    • Karin de Visser – Nether­lands Can­cer Insti­tute (NKI), The Netherlands
    • Car­olina Dive – Can­cer Research UK Man­ches­ter Insti­tute, UK
    • Rudolf Gross­chedl – Max Planck Insti­tute of Immuno­bi­ol­ogy and Epi­ge­net­ics, Germany
    • Tyler Jacks – Koch Insti­tute for Inte­gra­tive Can­cer Research at MIT, USA
    • Catri­ona Jamieson – Uni­ver­sity of Cal­i­for­nia, San Diego, USA
    • Jos Jonkers – Nether­lands Can­cer Insti­tute, The Netherlands
    • Laura Mach­esky – Can­cer Research UK, Beat­son Insti­tute, UK
    • Sean J. Mor­ri­son – The Uni­ver­sity of Texas South­west­ern Med­ical Cen­ter, USA
    • Luis Parada – UT South­west­ern, USA
    • Emmanuelle Passegué – Uni­ver­sity of Cal­i­for­nia, San Fran­cisco, USA
    • Daniel S. Peeper – Nether­lands Can­cer Insti­tute (NKI), The Netherlands
    • Pier Giuseppe Pelicci – Euro­pean Insti­tute of Oncol­ogy, IFOM-​IEO, Italy
    • Anjana Rao – La Jolla Insti­tute for Allergy & Immunol­ogy, USA
    • Julien Sage – Stan­ford School of Med­i­cine, USA
    • Ton Schu­macher – Nether­lands Can­cer Insti­tute (NKI), The Netherlands
    • Charles Swan­ton – The Fran­cis Crick Insti­tute, Uni­ver­sity Col­lege Lon­don, UK
    • Jean Zhao – Dana-​Farber Can­cer Insti­tute, USA


    • Sig­nalling path­ways in stroma and cancers
    • Can­cer stem cells
    • Can­cer and the immune system
    • Ani­mal mod­els of cancer
    • Ther­a­peu­ti­cal impli­ca­tions: from bench to bedside


    EMBL Advanced Train­ing Cen­tre Cor­po­rate Part­ner­ship Pro­gramme Reg­is­tra­tion Fee Waivers and EMBO Travel Grants are avail­able for young researchers for the EMBO | EMBL Sym­posia Series.

    Please indi­cate your inter­est when sub­mit­ting your abstract. Whilst sub­mit­ting your abstract you will also be asked to com­plete a field with the name of your lab and the coun­try in which it is based, and to answer some ques­tions to detail your rea­sons for request­ing this fel­low­ship. A state­ment of sup­port from your bud­get hold­ing super­vi­sor explain­ing a) their sup­port for your atten­dance and b) sup­port pro­vided by the lab­o­ra­tory bud­get is required to com­plete the application.

    Reg­is­tra­tion Fee Waiver: The sum that you have paid to attend the meet­ing will be reimbursed

    Travel Grant: Up to €500 for par­tic­i­pants arriv­ing from the eli­gi­ble coun­tries listed below

    Pri­or­ity is be given to par­tic­i­pants work­ing in labs in: Croa­tia, Czech Repub­lic, Esto­nia, Greece, Hun­gary, Italy, Malta, Poland, Por­tu­gal, Slo­va­kia, Slove­nia, Spain, Tai­wan and Turkey.

    Travel grants may also be pro­vided to par­tic­i­pants work­ing in labs in: Africa, Asia (exclud­ing Japan, Sin­ga­pore, and Korea), South and Cen­tral Amer­ica, Alba­nia, Arme­nia, Azer­bai­jan, Belarus, Bosnia and Herze­gov­ina, Bul­garia, Cyprus, Geor­gia, Kaza­khstan, Kosovo, Kyr­gyzs­tan, Latvia, Lithua­nia, Mace­do­nia, Moldova, Mon­tene­gro, Roma­nia, Russ­ian Fed­er­a­tion, Ser­bia and Ukraine.

    The sci­en­tific organ­is­ers will select the recip­i­ents of all fel­low­ships dur­ing the abstract selec­tion process.

    If you are awarded a fel­low­ship, you will be noti­fied after the com­ple­tion of the abstract selec­tion. This is usu­ally 8 weeks before the event start date. Please note that you must pay your reg­is­tra­tion fee by the pay­ment dead­line (6 weeks before the event start date). The EMBL Course & Con­fer­ence Office will reim­burse the reg­is­tra­tion fees after the event. Travel Grants can only be reim­bursed after the event once the receipts have been submitted.

    For sci­en­tists based in Sin­ga­pore addi­tional travel grants are avail­able. Travel grants are also avail­able as part of the coop­er­a­tion agree­ment with the National Sci­ence Coun­cil of Tai­wan, in addi­tion to travel grants for par­tic­i­pants from Italy in coop­er­a­tion with the SIBBM.

    For fur­ther infor­ma­tion about fel­low­ships please refer to the FAQ page.


    Organ­is­ing Committee

    Con­fer­ence Organiser

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