CardioVascular Clinical Trialists Asia Forum (CVCT) 2014 Singapore

  • Conference Call
  • You are kindly invited to par­tic­i­pate in the 2014 Car­dio­Vas­cu­lar Clin­i­cal Tri­al­ists Asia Forum (CVCT) which will be held on July 4 – 6, 2014 in Sin­ga­pore at the Fuller­ton Hotel Sin­ga­pore. This event is endorsed by the Sin­ga­pore Car­diac Soci­ety and the Asian Pacific Soci­ety of Car­di­ol­ogy.

    This inti­mate gath­er­ing of key opin­ion lead­ers assem­bled in the dynamic set­ting of Sin­ga­pore cre­ates the right envi­ron­ment for unpar­al­leled lev­els of sci­en­tific exchange and mutual learn­ing. Dur­ing the sci­en­tific ses­sions, work­shops and net­work­ing events, par­tic­i­pants will brain­storm on cur­rent issues in car­dio­vas­cu­lar drug, device and bio­marker devel­op­ment; and trial design, con­duct, ethics, inter­pre­ta­tion, approv­abil­ity and imple­men­ta­tion in Asia.

    The CVCT Asia Forum fol­lows the suc­cess­ful exam­ple of the main CVCT meet­ings in Paris which annu­ally enjoy large rep­re­sen­ta­tion from Europe and the US.

    Course Directors

    • Car­olyn Lam – Singapore
    • Faiez Zan­nad – France
    • Bertram Pitt – USA

    Course Direc­tors Board

    • Juliana Chan – Hong Kong
    • Mark Chan – Singapore
    • Shih-​Ann Chen – Taiwan
    • Chi Keong Ching – Singapore
    • Junbo Ge – China
    • Chu-​Pak Lau – Hong Kong
    • Houng Bang Liew – Malaysia
    • Hyo-​Soo Kim – Korea
    • Seung Jung Park – Korea
    • Kausik Ray – UK
    • Mark Richards – Singapore
    • Naoki Sato – Japan
    • Huay Cheem Tan – Singapore
    • Shu Zhang – China

    Forum Top­ics /​Speeches

    Day One

    Atrial fibrillation

    • Arrhyth­mia and anti­co­ag­u­la­tion tri­als in Asia: Nav­i­gat­ing reg­u­la­tory require­ments and keys to success
    • Arrhyth­mia and Device tri­als in Asia: Reg­u­la­tor Perspective
    • Bur­den of AF in Asia and local per­cep­tions of rate ver­sus rhythm control
    • Catheter abla­tion in AF: Asian experience
    • LAA clo­sure in AF: Asian experience
    • Oppor­tu­ni­ties, bar­ri­ers and chal­lenges for device ther­apy in Asia: Indus­try perspective
    • Reassess­ing stroke pre­ven­tion strate­gies: War­farin, NOACS or device therapies?

    Bio­marker Per­son­al­ized Medicine

    • Beyond the natri­uretic pep­tides: Which mark­ers should we study next and how?
    • Biomarker-​guided ther­apy tri­als: What have we learned and what is the future?
    • BNP and NT-​proBNP to guide ther­apy: Unan­swered questions
    • Pre­dic­tive bio­mark­ers. The future of HF per­son­al­ized medicine
    • Sta­tis­ti­cal cau­tions re the allure of per­son­alised medicine

    Car­diometa­bolic Trails

    • Bur­den of car­diometa­bolic dis­ease (DM, obe­sity, dys­lipi­demia) in Asia
    • Con­tex­tu­al­iza­tion of guide­lines for car­diometa­bolic dis­eases: Do we need ethnicity-​specific tri­als in Asia?
    • Dia­betes and car­dio­vas­cu­lar risk: impli­ca­tions of SAVOR-​TIMI and EXAM­INE for Asia
    • Eth­nic diver­sity in car­dio­vas­cu­lar risk
    • Fron­tiers and future car­diometa­bolic and car­dio­vas­cu­lar out­come tri­als in Asia: CRO perspective
    • Fron­tiers and future car­diometa­bolic tri­als in Asia: Clin­i­cian inves­ti­ga­tor perspective
    • Reg­u­la­tory issues in Clin­i­cal Tri­als: Dif­fer­ences between Euro­pean Med­i­cines Agency (EMA) and Food and Drug Admin­is­tra­tion (FDA)

    Heart Fail­ure Drug Trails

    • Acute heart fail­ure and hos­pi­tal­iza­tions in Asia: How reg­istry data can improve trial design
    • Diag­no­sis of HFpEF: Cur­rent and future guidelines
    • FAIR-​HF and FAIR-​HFpEF: Iron defi­ciency in HF
    • Fron­tiers and future tri­als in HF in Asia: Indus­try perspective
    • Fron­tiers and future tri­als in HF in Asia: Reg­u­la­tor perspective
    • PARA­MOUNT and PARAGON: Lessons learned
    • RELAX-​HF (Sere­laxin in acute HF): Lessons learned
    • SHIFT: Lessons learned
    • TOP­CAT: Lessons learned

    Heart Fail­ure Device Trails

    • Approval tracks in car­dio­vas­cu­lar tri­als: Per­spec­tives from expe­ri­ence with both Euro­pean (EMA) and Amer­i­can (FDA) reg­u­la­tors, and appli­ca­tions to Asia
    • Inter­na­tional CRT guide­lines: Exam­in­ing trial – based evi­dence and need for revision?
    • LBBB and QRS cut­offs in Asians: Need for ethnicity-​specific cri­te­ria for CRT?
    • MADIT-​CRT and beyond
    • Remote mon­i­tor­ing in HF: Applic­a­bil­ity and uptake in Asian health care systems
    • Sud­den Car­diac Death in Asians and progress in ICD ther­apy: New algo­rithms, pro­gram­ming, sub­cu­ta­neous ICDs


    Day Two

    Inter­ven­tional Car­di­ol­ogy Trails

    • Bioab­sorbable Poly­mer Deliv­ery and Bioab­sorbable Scaf­folds: Asia Pacific experience
    • Keys to suc­cess for inter­ven­tional tri­als in Asia Pacific: CRO perspective
    • Neural mod­u­la­tion inter­ven­tions (renal den­er­va­tion, vagal mod­u­la­tion, baros­tim­u­la­tion): Asia Pacific experience
    • Non-​blinded and/​or non-​randomised tri­als: when can they be trusted?
    • Per­cu­ta­neous valve inter­ven­tions (TAVR, mitr­a­clip): Asia Pacific experience
    • Sleep dis­or­dered breath­ing and car­dio­vas­cu­lar dis­ease in Asia
    • Tri­als update: ongo­ing tri­als in sleep dis­or­dered breathing

    Throm­bo­sis Trails

    • Anti­co­ag­u­la­tion in Asia: Are Asians are at higher risk of bleed­ing and do NOACs have an enhanced risk-​benefit profile?
    • Antiplatelet ther­apy: Prac­tice pat­terns and use of newer P2Y12 antag­o­nists across Asia
    • Car­dio­vas­cu­lar tri­als in Asia: ARO perspective
    • New Anti-​thrombotic Agents in PCI: Aptamers and More
    • Throm­bo­sis tri­als in Asia: Indus­try perspective
    starting: ending: 06.07.2014 Location: , Category:

    Timeline

    Conference START 06.07.2014 END

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